Endoglin antibody

Catalog No. ABIN7670052

This Mouse Monoclonal antibody specifically detects Endoglin in FACS. It exhibits reactivity toward Human.

Quick Overview for Endoglin antibody (ABIN7670052)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: SN6

Product Details anti-Endoglin Antibody

Purpose: Purified Anti-Human CD105 Antibody[SN6]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background: HHT,RP11 228B,Osler Rendu Weber syndrome,END,HHT1,ORW1,CD105,ENG,endoglin,AI528660,AI662476,CD 105,CD105 antigen,EGLN,FLJ41744,ORW,Osler Rendu Weber syndrome 1,RP11 228B15.2,S-endoglin,SN6,AI528660,AI662476,CD 105,CD105,CD105 antigen,EGLN,END,Endoglin,Eng,FLJ41744,HHT1,ORW,ORW1,Osler Rendu Weber syndrome 1,RP11 228B15.2,S-endoglin,SN6,ENG,END,Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71 % aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells.

UniProt: P17813